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Endocrinology-metabolism
Elevated lipoprotein(a) levels predict cardiovascular disease in type 2 diabetes mellitus: a 10-year prospective cohort study
Tae-Seok Lim, Jae-Seung Yun, Seon-Ah Cha, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn, Yong-Moon Park, Seung-Hyun Ko
Korean J Intern Med. 2016;31(6):1110-1119. Published online October 18, 2016
Background/Aims: Elevated lipoprotein(a) (Lp[a]) level is known to be a risk factor for cardiovascular disease (CVD). However, the data that has been reported on the association between the Lp(a) level and CVD in type 2 diabetes has been limited and incoherent. The aim of this study was to investiga..
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Poor glycemic control is associated with the risk of subclinical hypothyroidism in patients with type 2 diabetes mellitus
Jae Ho Cho, Ho Jin Kim, Jun Ho Lee, Il Rae Park, Jun Sung Moon, Ji Sung Yoon, In-Kyu Lee, Kyu Chang Won, Hyoung Woo Lee
Korean J Intern Med. 2016;31(4):703-711. Published online June 8, 2016
Background/Aims: Overt hypothyroidism is frequently found in patients with type 2 diabetes mellitus (T2DM), but it remains unknown the relationship between subclinical hypothyroidism (SCH) and T2DM. We attempt to evaluate the difference in prevalence of SCH between patients with T2DM and general pop..
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Blood electrolyte disturbances during severe hypoglycemia in Korean patients with type 2 diabetes
Mi Yeon Kang
Korean J Intern Med. 2015;30(5):648-656. Published online August 27, 2015
Background/Aims: To investigate abnormalities in blood electrolyte levels during severe hypoglycemia in Korean patients with type 2 diabetes mellitus (T2DM) in a clinical setting.
Methods: Blood electrolyte levels in adult T2DM patients during severe hypoglycemia were collected from January 1, 200..
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The effect of high-dose vitamin D supplementation on insulin resistance and arterial stiffness in patients with type 2 diabetes
Ohk-Hyun Ryu, Wankyo Chung, Sungwha Lee, Kyung-Soon Hong, Moon-Gi Choi, Hyung Joon Yoo
Korean J Intern Med. 2014;29(5):620-629. Published online August 28, 2014
Background/Aims: Recent epidemiological studies revealed a striking inverse relationship between vitamin D levels, glucose intolerance/insulin resistance (IR), and cardiovascular disease. However, few interventional studies have evaluated the effect of vitamin D supplementation on cardiovascular ris..
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Nephrology
Renal outcomes and clinical course of nondiabetic renal diseases in patients with type 2 diabetes
Ja Min Byun, Cheol Hyun Lee, Sul Ra Lee, Ju Young Moon, Sang Ho Lee, Tae Won Lee, Chun Gyoo Ihm, Kyung Hwan Jeong
Korean J Intern Med. 2013;28(5):565-572. Published online August 14, 2013
Background/AimsIn several recent studies, renal biopsies in patients with type 2 diabetes and renal disease have revealed a heterogeneous group of disease entities. Our aim was to study the prognosis and clinical course of nondiabetic renal disease (NDRD) and to determine risk..
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Associations between Hemoglobin Concentrations and the Clinical Characteristics of Patients with Type 2 Diabetes
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2012;27(3):285-292. Published online September 1, 2012
Background/AimsMany studies have demonstrated an association between hemoglobin levels and cardiovascular disease in diabetic patients. The aim of this study was to determine whether there is an association between hemoglobin concentrations and various clinical parameters, inc..
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Comorbidity Study on Type 2 Diabetes Mellitus Using Data Mining
Hye Soon Kim, A Mi Shin, Mi Kyung Kim, Yoon Nyun Kim
Korean J Intern Med. 2012;27(2):197-202. Published online May 31, 2012
Background/AimsThe aim of this study was to analyze comorbidity in patients with type 2 diabetes mellitus (T2DM) by using association rule mining (ARM). MethodsWe used data from patients who visited Keimyung University Dongsan Medical Center fro..
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Associations among Body Mass Index, Insulin Resistance, and Pancreatic β-Cell Function in Korean Patients with New-Onset Type 2 Diabetes
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2012;27(1):66-71. Published online February 28, 2012
Background/AimsWe investigated the associations among body mass index (BMI), insulin resistance, and β-cell function in Korean patients newly presenting with type 2 diabetes. MethodsIn total, 132 patients with new-onset type 2 diabetes mellitu..
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Validity of Glycated Hemoglobin in Screening and Diagnosing Type 2 Diabetes Mellitus in Chinese Subjects
Yun Yu, Xiao-Jun Ouyang, Qing-Lin Lou, Liu-Bao Gu, Yong-Zhen Mo, Gary T. Ko, Chun-Chung Chow, Wing-Yee So, Ronald Ma, Alice Kong, Nicola Brown, Jennifer Nan, Juliana Chan, Rong-Wen Bian
Korean J Intern Med. 2012;27(1):41-46. Published online February 28, 2012
Background/AimsThe application of glycated hemoglobin (HbA1c) for the diagnosis of diabetes is currently under extensive discussion. In this study, we explored the validity of using HbA1c as a screening and diagnostic test in Chinese subjects recruited in..
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Sleep Disorder and Cardiovascular Risk Factors among Patients with Type 2 Diabetes Mellitus
Unjin Shim, Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2011;26(3):277-284. Published online September 13, 2011
Background/AimsSleep disorder (SD) is associated with an increased risk of cardiovascular disease and is more prevalent among individuals with type 2 diabetes mellitus. These health problems not only frequently coexist but also exacerbate each other. We conducted a cross-secti..
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The Effect of Early Insulin Therapy on Pancreatic β-Cell Function and Long-Term Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients
Suk Chon, Seungjoon Oh, Sung Woon Kim, Jin-Woo Kim, Young Seol Kim, Jeong-taek Woo
Korean J Intern Med. 2010;25(3):273-281. Published online August 31, 2010
Background/AimsBased on the results of well designed clinical studies, intensive insulin therapy has been established to improve glycemic control in newly diagnosed diabetes. However, discrepancies exist between the findings of clinical trials and experiences in general pract..
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Familial Clustering of Type 2 Diabetes in Korean Women with Gestational Diabetes Mellitus
Sang Youl Rhee, Joo Young Kim, Jeong-Taek Woo, Young Seol Kim, Sung-Hoon Kim
Korean J Intern Med. 2010;25(3):269-272. Published online August 31, 2010
Background/AimsThis study was conducted to examine the relationship between family history of type 2 diabetes (T2DM) and risk of developing gestational diabetes mellitus (GDM) in Korean women. MethodsWe performed a 100-g oral glucose tolerance t..
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The Prevalence of Gastrointestinal Symptoms in Patients with Non-Insulin Dependent Diabetes Mellitus
Jung-Hwan Oh, Myung-Gyu Choi, Moo-Il Kang, Kang-Moon Lee, Jin Il Kim, Byung-Wook Kim, Dong-Soo Lee, Sung-Soo Kim, Hwang Choi, Sok-Won Han, Kyu-Yong Choi, Ho-Young Son, In-Sik Chung
Korean J Intern Med. 2009;24(4):309-317. Published online November 27, 2009
Background/AimsGastrointestinal (GI) symptoms are common among patients with non-insulin dependent diabetes mellitus (NIDDM). Our aim was to investigate the frequency of chronic GI symptoms in Korean patients with NIDDM. MethodsA cross-sectiona..
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Early Detection Of Asymptomatic Coronary Artery Disease In Patients With Type 2 Diabetes Mellitus
Won Sang Yoo, Hee Jin Kim, Dohee Kim, Myung Yong Lee, Hyun-Kyung Chung
Korean J Intern Med. 2009;24(3):183-189. Published online August 26, 2009
Background/AimsIn type 2 diabetic patients, coronary artery disease (CAD) is usually detected at an advanced stage due to a lack of symptoms. The aim of this study was to define which clinical parameters or non-invasive tests predict CAD in asymptomatic type 2 diabetic patients..
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